Key Highlights Werdnig Hoffmann Disease, also known as Spinal Muscular Atrophy Type 1 (SMA1), is a severe genetic disorder that affects muscle control. Scoliosis, a sideways curvature of the spine, commonly occurs in children with Werdnig Hoffmann Disease due to muscle weakness. Early diagnosis and treatment are critical for managing both conditions and improving quality of life. New advancements in gene therapy and disease-modifying therapies...

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Key Highlights Riley-Day Syndrome, or Familial Dysautonomia, is a rare genetic disorder that affects the nervous system. This condition can lead to various symptoms, and some individuals with Riley-Day Syndrome may also develop scoliosis. Scoliosis, a sideways curvature of the spine, can range from mild to severe and may require different treatment approaches. Diagnosing the dual presence of Riley-Day Syndrome and scoliosis involves a combination...

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Key Highlights Scoliosis, a sideways curvature of the spine, can be linked to neurological disorders like Friedreich's Ataxia (FA). FA is a genetic condition causing progressive nervous system damage, leading to muscle weakness, balance problems, and other issues. The lack of the protein frataxin in FA affects the nervous system and muscles, leading to spinal curvature. Diagnosing scoliosis in FA patients involves physical exams, genetic...

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